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Table 2 Expression of surface HLA class I, HLA class II and ICAM-1 by nontransduced and IFN-γ-transduced NPC cell lines as determined by cytofluorometric analysis

From: Differential baseline and response profile to IFN-γ gene transduction of IL-6/IL-6 receptor-α secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture

Cell line/Subline

HLA class I

HLA class II

ICAM-1

Derived from primary lesion

   

NPC039

   

   Nontransduced

99.9 (73.0) *

0.4

99.7 (22.1)

   Transduced

99.3 (231.8)

40.1 (22.0)

99.3 (61.1)

NPC076

   

   Nontransduced

97.9 (96.8)

0.1

93.2 (16.8)

   Transduced

94.1 (147.3)

28.4 (30.8)

90.8 (44.7)

NPC-BR

   

   Nontransduced

95.8 (78.7)

0.5

95.9 (25.4)

   Transduced

97.9 (139.7)

48.7 (36.2)

96.7 (50.2)

NPC039-2E2 §

   

   Nontransduced

99.9 (138.8)

0.1

86.9 (13.5)

   Transduced

99.9 (179.5)

72.4 (44.0)

96.6 (30.5)

NPC039-6A1 §

   

   Nontransduced

89.5 (71.6)

2.3 (8.2)

79.1 (13.6)

   Transduced

97.6 (283.0)

48.8 (47.7)

86.0 (27.3)

NPC039-7B2 §

   

   Nontransduced

99.6 (44.3)

0.9 (6.8)

90.7 (10.2)

   Transduced

98.8 (88.7)

39.5 (58.0)

95.3 (23.9)

Derived from bone marrow metastasis

   

NPC-BM1

   

   Nontransduced

91.2 (55.3)

26.2 (28.8)

87.8 (26.9)

   Transduced

96.8 (97.6)

41.9 (28.2)

91.7 (28.8)

NPC-BM3

   

   Nontransduced

89.4 (78.2)

18.6 (33.4)

87.1 (19.6)

   Transduced

93.1 (121.6)

66.7 (50.5)

93.8 (49.2)