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Figure 3 | BMC Cancer

Figure 3

From: Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma

Figure 3

Staining of three predicted miR-21 target genes in normal, FEA, DCIS and IDC tissue. PTEN showed nuclear staining and was expressed strongly in normal, FEA, DCIS and IDC. TM1 expression in normal, FEA, DCIS and IDC showed cytoplasmic staining and there was a decrease from normal to FEA, DCIS and IDC. PDCD4 was expressed mainly in nuclei in normal breast while the staining pattern gradually shifted from nuclear to cytoplasmic in FEA, DCIS and IDC (400× magnification for all).

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