Figure 1
From: IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells
IGF-I activate caspases 3/7, 8 and 9 in HT-29 cells.IGF-I activate caspases 3/7 (a, b, g, h), 8 (c, d, i, j) and 9 (e, f, k, l) in HT-29 cells in serum containing (SCM, a-f) and serum free (SFM, g-l) media following the treatment with different concentrations of IGF-I (1, 10, and 100 ng/ml) for 24 and 48 hours. Significance value: * P <0.05; ** P <0.01 compared to untreated cells.