Table 2 Frequency of 5'-UTR loss of heterozygosity (LOH) in low esophagus, IM, dysplasia and BA tissues
Low esophagus (LE) (n = 37) | Â | Â | Â | Â | Â |
|---|---|---|---|---|---|
Genotype in normal tissues | 2R/2R | 2R/3R | 3R/3R | ||
Number of samples | 8 | 22 | 7 | ||
Genotype in LE tissues | Â | 2R/loss | 2R/3R | 3R/loss | Â |
Number of samples | Â | 0 | 22 | 0 | Â |
Frequency | Â | 0% | 100% | 0% | Â |
Intestinal metaplasia (IM) (n = 29) | Â | Â | Â | Â | Â |
Genotype in normal tissues | 2R/2R | 2R/3R | 3R/3R | ||
Number of samples | 3 | 21 | 5 | ||
Genotype in IM tissues | Â | 2R/loss | 2R/3R | 3R/loss | Â |
Number of samples | Â | 5 | 15 | 1 | Â |
Frequency | Â | 23.80% | 71.40% | 4.80% | Â |
Dysplasia (n = 13) | Â | Â | Â | Â | Â |
Genotype in normal tissues | 2R/2R | 2R/3R | 3R/3R | ||
Number of samples | 4 | 7 | 2 | ||
Genotype in dysplasia tissues | Â | 2R/loss | 2R/3R | 3R/loss | Â |
Number of samples | Â | 1 | 5 | 1 | Â |
Frequency | Â | 14.30% | 71.40% | 14.30% | Â |
Barrett associated adenocarcinoma (BA) (n = 44) | Â | Â | Â | Â | Â |
Genotype in normal tissues | 2R/2R | 2R/3R | 3R/3R | ||
Number of samples | 15 | 25 | 4 | ||
Genotype in BA tissues | Â | 2R/loss | 2R/3R | 3R/loss | Â |
Number of samples | Â | 3 | 15 | 7 | Â |
Frequency | Â | 12% | 60% | 28% | Â |