Loss of heterozygosity at thymidylate synthase locus in Barrett's metaplasia, dysplasia, and carcinoma sequences

BMC Cancer

Table 1 Patient characteristics

The number of patients	100
Male	73
Female	27
Age (median)	65
Pathological type (in descending order of)
Reflux esophagitis	30
Intestinal metaplasia	22 (※)
Dysplasia	4
Barrett's adenocarcinoma	44 (※※)
Race
Caucasian	89
Asian	6
Hispanic	3
African-American	1
Native American	1
TS genotype in normal tissue
2R/2R	24
2R/3R	57
3R/3R	19

※ Including 4 patients from each of whom 2 samples of different diseased tissues were taken (e.g: reflux esophagitis and intestinal metaplasia).
※※ Including 9 patients from each of whom 2 samples of different diseased tissues were taken, and 5 patients from each of whom 3 were taken.

ISSN: 1471-2407