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Table 2 Correlation between the IL-6, CRP and clinicopathological parameters

From: Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer

  IL-6 CRP
  Median ± SD r P Median ± SD R P
Total pg/ml    (mg/dl)   
Gender       
   Male 6.83 ± 7.34 0.082 0.385 0.11 ± 0.25 -0.076 0.421
   Female 7.07 ± 12.30    0.06 ± 0.43   
Age       
   <60 6.48 ± 12.26 0.205 0.028 0.07 ± 0.30 0.152 0.104
   ≥ 60 7.31 ± 5.56    0.11 ± 0.38   
Tumor size       
   <5 cm 6.48 ± 5.04 0.235 0.012 0.09 ± 0.28 0.081 0.389
   ≥5 cm 7.56 ± 12.93    0.09 ± 0.39   
Tumor depth       
   pT1 6.25 ± 1.41 0.387 0.000 0.05 ± 0.10 0.311 0.001
   pT2 6.60 ± 5.42    0.07 ± 0.31   
   pT3 7.62 ± 16.02    0.17 ± 0.36   
   pT4 9.76 ± 6.06    0.64 ± 0.64   
LN meta       
   N0 6.36 ± 5.61 0.322 0.000 0.06 ± 0.30 0.211 0.024
   N1 7.70 ± 13.99    0.11 ± 0.36   
   N2 6.83 ± 2.10    0.09 ± 0.08   
   N3 7.80 ± 6.96    0.19 ± 0.51   
   (N1–N3) 7.56 ± 11.24 0.338 0.000 0.11 ± 0.35 0.212 0.023
TNM stage       
   I 7.36 ± 5.52 0.425 0.000 0.06 ± 0.29 0.326 0.000
   II 7.66 ± 2.24    0.07 ± 0.15   
   III 11.87 ± 14.90    0.12 ± 0.30   
   IV 13.92 ± 10.76    0.39 ± 0.50   
Peritoneal       
   Metastasis(-) 6,83 ± 8.83 0.233 0.012 0.08 ± 0.29 0.175 0.061
   Metastasis(+) 23.70 ± 14.55    0.41 ± 0.69   
  1. r, P: Spearman rho correlation, IL-6: interleukin-6, CRP: C-reactive protein, LN: lymph node, TNM (6th AJCC Stage Groupings: The staging systems; Primary tumor, regional LN, metastasis)