Table 5 Logistic regressions for association between leucopenia, anaemia and thrombocytopenia and B symptoms and other potential predictor variables.

Leucopenia *

B symptoms present

2.0 (1.5–2.8)

< 0.001

1.7 (1.2–2.4)

0.005

Performance status level 2–4

3.0 (2.1–4.3)

< 0.001

2.2 (1.5–3.3)

< 0.001

Bone marrow aspirate positive

2.3 (1.3–4.1)

0.006

2.2 (1.2–4.0)

0.015

Age 75 years or older

1.8 (1.3–2.6)

0.001

2.1 (1.4–3.1)

< 0.001

PMitCEBO given

2.4 (1.7–3.3)

< 0.001

2.1 (1.5–3.0)

< 0.001

GCSF given

0.6 (0.4–0.8)

0.001

0.5 (0.4–0.8)

0.001

Bone marrow trephine positive

2.1 (1.3–3.4)

0.002

-

Stage 3 or 4

1.8 (1.3–2.5)

< 0.001

-

LDH elevated

1.4 (1.02–2.0)

0.038

-

Anaemia **

B symptoms present

2.3 (1.2–4.3)

0.013

2.3 (1.1–4.7)

0.025

LDH elevated

2.9 (1.3–6.7)

0.011

2.6 (1.1–6.1)

< 0.001

GCSF given

2.6 (1.3–4.9)

0.004

2.3 (1.1–4.5)

0.020

Bone marrow aspirate positive

2.5 (1.1–5.8)

0.030

-

Performance status level 2–4

2.1 (1.2–3.9)

0.013

-

Bone marrow trephine positive

1.9 (0.9–4.1)

0.088

-

Thrombocytopenia ***

B symptoms present

2.7 (1.5–4.8)

0.001

-

Performance status level 2–4

4.8 (2.8–8.2)

< 0.001

4.8 (2.5–9.2)

< 0.001

LDH elevated

6.7 (2.6–17.0)

< 0.001

4.0 (1.5–10.4)

0.005

Bone marrow trephine positive

2.8 (1.5–5.2)

0.001

2.9 (1.4–5.8)

0.003

PMitCEBO given

0.6 (0.4–1.0)

0.058

0.5 (0.3–0.9)

0.032

Stage 3 or 4

3.2 (1.6–6.2)

0.001

-

Bone marrow aspirate positive

2.7 (1.4–5.6)

0.005

-

Age 75 years or older

2.0 (1.2–3.4)

0.011

-

GCSF given

1.7 (1.0–2.8)

0.058

-