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Table 1 Characteristics of patients

From: δ-ALA-D activity is a reliable marker for oxidative stress in bone marrow transplant patients

Number of patients (n = 37) Autologous PBSCT group II (n = 13) Allogeneic BMT group III (n = 24)
Mean age (years) 48.15 ± 12.67b 36.00 ± 16.08
   Male 10 12
   Female 03b 12
Diagnosis   
   Multiple myeloma 03 01
   Lymphoma Hodgkin 05 03
   Lymphoma No Hodgkin 02 02
   Leukemia   
   Leukemia Acute myeloid 01 02
   Leukemia Chronic myeloid 00 07
   Leukemia Acute lymphoblastic 01 01
   Leukemia Chronic lymphoid 00 01
   Myelodysplasia 00 05
Aplastic anemia 00 02
Tumor Ewing 01 00
Conditioning regimen   
   BuCy 120 01 13
   BuCy 200 01 00
   M-200 04 01
   CBV 04 00
   FluCy 00 05
   BEAM 02 00
   CyTBI 01 03
   another 00 02
  1. The CR patients were divided according to diseases. M-200: melphalan (200 mg/m2) given only 1 day (day minus 3) before the transplantation for multiple myeloma in autologous peripheral blood stem cell transplantation (PBSCT) or allogeneic BMT. CBV: cyclophosphamide (1500 mg/m2) given 4 consecutive days starting 6 days before the transplantation (days minus 6 to minus 3) + carmustine (BCNU – 450 mg/m2) given only 1 day before the transplantation (day minus 6) + etoposide (VP-16 – 250 mg/m2) given 3 consecutive days two times a day, starting 6 days before the transplantation (days minus 6 to minus 4) or BEAM: carmustine (BCNU – 300 mg/m2) given only 1 day before the transplantation (day minus 7) + etoposide (VP-16 – 200 mg/m2) given 4 consecutive days two times a day, starting 6 days before the transplantation (days minus 6 to minus 3) + cytarabine (100 mg/m2) given 4 consecutive days two times a day, starting 6 days before the transplantation (days minus 6 to minus 3) + melphalan (140 mg/m2) given only 1 day before the transplantation (day minus 6) for Hodgkin and non-Hodgkin lymphomas in autologous PBSCT. FluCy: fludarabine (30 mg/m2) + cyclophosphamide (300 mg/m2), both given 3 consecutive days, starting 4 days before the transplantation (days minus 4 to minus 2) for Hodgkin and non-Hodgkin lymphomas in allogeneic BMT. BuCy120: busulphan (1 mg/kg), given 4 consecutive days four times a day, starting 8 days before the transplantation (days minus 8 to minus 5) + cyclophosphamide (60 mg/kg), given 2 consecutive days, starting 4 days before the transplantation (days minus 4 to minus 3) for acute and chronic myeloid leukemia and syndrome mielodysplastic in autologous PBSCT or allogeneic BMT. BuCy200: busulphan (1 mg/kg), given 3 consecutive days four times a day, starting 9 days before the transplantation (days minus 9 to minus 7) + cyclophosphamide (50 mg/m2), given 4 consecutive days, starting 6 days before the transplantation (days minus 6 to minus 3) for aplastic anemia in allogeneic BMT. CyTBI: cyclophosphamide (60 mg/m2), given 2 consecutive days, starting 7 days before the transplantation (days minus 7 to minus 6) + total body irradiation, carried out on 4 consecutive days, starting 4 days before the transplantation (days minus 4 to minus 2, three times a day and day minus 1, two times a day) for acute and chronic lymphoid leukemia in autologous PBSCT or allogeneic BMT. All patients had 2 rest days (without chemotherapy) before the transplantation (days minus 2 and minus 1), except FluCy and CyTBI CR patients, that had only one rest day (day minus 1 and minus 5, respectively).
  2. b Significantly different between groups II (autol.) and III (allog.).