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Table 3 Pairwise haplotype frequencies in SCCHN patients and controls.

From: A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population

  No. alleles Estimated haplotype frequency D'
   ‡ 1 - 1 1 - 2^ 2 - 1 2 - 2  
Intron 3-exon 4 †       
Cases 566 0.740 0.052 0.086 0.120 0.61
Controls 590 0.716 0.030 0.120 0.131 0.74
Intron 3-intron 6†       
Cases 566 0.772 0.055 0.058 0.115 0.61
Controls 590 0.763 0.074 0.035 0.128 0.73
Exon 4-intron 6*       
Cases 566 0.744 0.049 0.086 0.121 0.64
Controls 590 0.719 0.026 0.076 0.176 0.83
  1. p-value of χ2-test: cases versus controls > 0.1
  2. * p-value < 0.001
  3. ‡ 1 = intron 3 (W), exon 4 Arg, intron 6 G
  4. ^ 2 = intron (M), exon 4 Pro, intron 6 A