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Table 3 Pairwise haplotype frequencies in SCCHN patients and controls.

From: A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population

 

No. alleles

Estimated haplotype frequency

D'

  

‡ 1 - 1

1 - 2^

2 - 1

2 - 2

 

Intron 3-exon 4 †

      

Cases

566

0.740

0.052

0.086

0.120

0.61

Controls

590

0.716

0.030

0.120

0.131

0.74

Intron 3-intron 6†

      

Cases

566

0.772

0.055

0.058

0.115

0.61

Controls

590

0.763

0.074

0.035

0.128

0.73

Exon 4-intron 6*

      

Cases

566

0.744

0.049

0.086

0.121

0.64

Controls

590

0.719

0.026

0.076

0.176

0.83

  1. † p-value of χ2-test: cases versus controls > 0.1
  2. * p-value < 0.001
  3. ‡ 1 = intron 3 (W), exon 4 Arg, intron 6 G
  4. ^ 2 = intron (M), exon 4 Pro, intron 6 A