Skip to main content

Table 2 MDM2 SNP309 genotype and allele frequencies of Taiwanese breast cancer cases and healthy controls

From: Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer

 

MDM2 SNP309a

Frequency

Cases, n(%)

Controls, n(%)

Entire cohort n(%)b

Genotype

   

TT

18 (14.5)

25 (25.8)

43 (19.4)

TG

80 (64.5)

56 (57.7)

136 (61.7)

GG

26 (21)

16 (16.5)

42 (18.9)

TG+GG

106 (85.5)

72 (74.2)

179 (80.6)

Allele

   

T

0.468

0.541

0.498

G

0.532

0.459

0.502

  1. aThe χ2 of cases, controls and entire cohort are 10.84, 2.63, and 12.18, respectively. Degree of freedom (d.f.) = 2
  2. b Entire cohort is the sum of each genotype in breast cancer cases and healthy controls.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us