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Table 2 MDM2 SNP309 genotype and allele frequencies of Taiwanese breast cancer cases and healthy controls

From: Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer

  MDM2 SNP309a
Frequency Cases, n(%) Controls, n(%) Entire cohort n(%)b
Genotype    
TT 18 (14.5) 25 (25.8) 43 (19.4)
TG 80 (64.5) 56 (57.7) 136 (61.7)
GG 26 (21) 16 (16.5) 42 (18.9)
TG+GG 106 (85.5) 72 (74.2) 179 (80.6)
Allele    
T 0.468 0.541 0.498
G 0.532 0.459 0.502
  1. aThe χ2 of cases, controls and entire cohort are 10.84, 2.63, and 12.18, respectively. Degree of freedom (d.f.) = 2
  2. b Entire cohort is the sum of each genotype in breast cancer cases and healthy controls.