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Table 2 IAPs, XAF1, Smac/DIABLO normalized mRNA level and ratios.

From: Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma

  Non neoplasia Hepatocarcinoma Fold Change p value*
NAIP (BIRC1) 1,24 (0,01–2,6) 0,82 (0,0004–3,6) 0,67  
c-IAP1 (BIRC2) 2,13 (0.06–5.5) 1,94 (0.01–5.8) 0,91  
c-IAP2 (BIRC3) 1,23 (0.1–6.1) 1,21 (0.04–5.9) 0,99  
XIAP (BIRC4) 0,86 (0.3–2.5) 0,99 (0.06–2.2) 1,15  
Survivin (BIRC5) 0,03 (0.03–0.1) 0,20 (0.1–1.6) 6,86 1·10–6
Bruce (BIRC6) 1,36 (0.06–5.9) 1,36 (0.02–3.3) 1,00  
Livin/ML-IAP (BIRC7) 0,13 (0.01–1.5) 0,31 (0.01–3.6) 2,33 6·10–3
XAF1 (BIRC4BP) 0,69 (0.1–2.4) 0,61 (0.07–3.9) 0,88  
Smac/DIABLO 1,03 (0.4–2.1) 1,13 (0.4–3.6) 1,10  
Ratio XIAP/XAF1 2,29 (0.3–12.9) 6,90 (0.2–47.0) 3,02 3·10–4
Ratio XIAP/Smac/DIABLO 0,92 (0.04–2.0) 1,00 (0.01–4.2) 1,09  
  1. * Student t-test.