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Table 2 Summary of ORs for various comparisons

From: Association between the NBS1E185Q polymorphism and cancer risk: a meta-analysis

E185Q

comparison*

Population (number of data sets)§

Fixed-effects OR(95%CI)

Random-effects OR(95%CI)

Heterogeneity (P value Q test)

P value

(fixed)

P value

(random)

(GC+CC) vs GG

17

1.06(1.00–1.12)

1.06(1.00–1.12)

0.54

0.05

0.05

CC vs GG

16

0.99(0.90–1.09)

0.98(0.85–1.13)

0.02

0.83

0.78

CC vs (GC +GG)

16

0.95(0.87–1.04)

0.94(0.82–1.07)

0.03

0.28

0.36

C vs G

16

1.02(0.97–1.08)

1.02(0.98–1.07)

0.10

0.45

0.36

  1. *Additive genetic model: CC vs GG, recessive genetic model: CC vs (GC +GG), dominant genetic model: (GC+CC) vs GG
  2. §Ryk's study was not involved in 16 studies.