Figure 1From: Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation Fluorescence emission spectrum of BSP-treated proMMP-2. proMMP-2 (333 nM) was incubated with increasing concentrations of native or recombinant BSP, OPN or RNase A (negative controls). Emission scans were obtained after each addition of BSP (excitation wavelength of 295 nm). In all cases, titrations of proMMP-2 yielded proportional quenching of the proMMP-2 tryptophan emission spectra.Back to article page