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Table 1 Baseline patient characteristics

From: Brain metastasis development and poor survival associated with carcinoembryonic antigen (CEA) level in advanced non-small cell lung cancer: a prospective analysis

N = 293

Mean ± SE

Patients

(%)

Age (years)

60.7 ± 0.7

 

Gender

  

   Female

 

44

   Male

 

56

Smoking History

  

   Positive

 

53.9

   Negative

 

46.1

ECOG

  

   1

 

45.4

   2

 

23.5

   3

 

31.1

Clinical Stage

  

   III B

 

29.4

   IV

 

70.6

Histology

  

   Adenocarcinoma

 

64.8

   *Other

 

35.2

Histological Grade

  

   Low

 

10.3

   Moderate

 

35.9

   High

 

53.8

Metastasis at Diagnosis

  

   CNS

 

18.6

   Liver

 

7.5

   **Other

 

44.9

First Line Treatment

  

   Chemotherapy

 

87.4

   Tyrosine-kinase inhibitors

 

12.6

EGFR***

  

   Positive

 

58.6

   Negative

 

41.4

HER2***

  

   Positive

 

6.8

   Negative

 

93.2

  1. SE: Standard Error.
  2. ECOG: Eastern Oncology Cooperative Group Scale.
  3. *Other: Squamous, Giant Cells, Undifferentiated.
  4. CNS: Central Nervous System.
  5. **Other: Lymph Nodes, Bones, Contralateral Lung.
  6. EGFR: Epidermal Growth-Factor Receptor.
  7. ***: Tissue expression was determined only in 85 different
  8. primary tumor samples (see text).