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Table 3 Differentially expressed genes associated with cervical lymph node and pathologic stage status

From: Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis

p-value Number present t-score Accession: Definition/Description or EST name
0.001% 30 5.324 M20681: Human glucose transporter-like protein-III (Glu3)
0.006% 10 4.525 X71125: H. sapiens mRNA for glutamine cyclotransferase
0.011% 10 3.943 X51757: HAP70B Human heat-shock protein HSP70B gene
0.014% 16 4.519 AB028957: H. sapiens mRNA for KIAA1034 protein
0.025% 26 4.261 Protein Phosphatase inhibitor homolog
0.021% 30 4.568 Y12065: H. Sapiens mRNA for nucleolar protein hNop56
0.031% 29 4.272 AB015633: Homo sapiens mRNA for type II membrane protein
0.031% 8 4.517 D78579: Homo sapiens mRNA for neuron derived orphan receptor
0.031% 17 3.764 W25985: 17e6
0.044% 31 3.792 AF007140: Homo sapiens clone 23711 unknown mRNA
0.061% 31 3.659 X86163: H. sapiens mRNA for B2-bradykinin receptor
0.064% 31 3.706 A1935420: wo84c08
0.076% 8 3.188 AB020654: Homo sapiens mRNA for KIAA0847 protein
0.076% 7 3.246 L23959: HUMDP1A Homo sapiens E2F-related transcription factor (DP-1) mRNA
0.090% 31 2.808 AL09674: Homo sapiens mRNA: cDNA DKFZp58600223
0.090% 21 3.544 Z11697: Homo sapiens mRNA for HB 15
0.090% 22 3.813 X98834: H. sapiens mRNA for zinc finger protein, Hsal2
0.106% 16 3.720 M81750: H. sapiens myeloid cell nuclear differentiation antigen mRNA
0.106% 25 3.943 S68134: CREM = cyclic AMP-responsive element modulator beta isoform
0.125% 31 3.302 X98296: H. sapiens mRNA for ubiquitin hydrolase
0.147% 26 3.051 U49392: Human allograft inflammatory factor-1 (AIF-1) mRNA
0.193% 7 3.269 AL109669: Homo sapiens mRNA full length insert cDNA clone EUROIMAGE
0.195% 5 2.861 M31166: HUMTSG14A Human tumor necrosis factor-inducible (TSG-14) mRNA
A    
p-value Number present t-score Accession: Definition/Description or EST name
0.016% 31 4.286 AA402538: Soares ovary tumor NbHOT Homo sapiens cDNA
0.035% 22 3.690 X98834: H. sapiens mRNA for zinc finger protein, Hsal2
0.035% 26 3.501 U49392: Human allograft inflammatory factory-1 (ALF-1) mRNA
0.043% 5 3.782 X62055: H. sapiens PTP1C mRNA for protein-tyrosine phosphate
p-value Number present t-score Accession: Definition/Description or EST name
0.062% 11 3.514 AB023135: Homo sapiens mRNA for activation-inducible lymphocyte
    immunomediatory molecule AILIM
0.062% 31 3.698 A1828166: wk32h09
0.073% 31 3.761 U85773: Human phosphomannomutase (PMM2) mRNA
0.085% 6 3.501 S67970: ZNF75 = KRAB zinc finger [human, lung fibroblast, mRNA
0.104% 16 3.709 M81750: H. sapiens myeloid cell nuclear differentiation antigen mRNA
0.104% 31 3.824 AA121509:zk88c10.s1
p-value Number present t-score Accession: Definition/Description or EST name
0.104% 21 3.023 Z11697: Homo sapiens mRNA for HB15
0.104% 31 3.952 D67031: Homo sapiens ADDL mRNA for adducin-like protein
0.123% 29 3.565 J02923: Human 65-kilodalton phosphoprotein (p65) mRNA
0.123% 21 3.271 L10717: Homo sapiens T cell-specified tyrosine kinase mRNA
0.145% 26 2.955 AL031228:dJ1033B10. 10/Membrane protein with histidine rich charge clusters
0.145% 24 3.512 AB011102: Homo sapiens mRNA for KIAA0530 protein
0.170% 25 2.843 M80482: Human subtilisin-like protein (PACE4) mRNA
0.199% 19 3.215 AF072099: Homo sapiens immunoglobulin-like transcript 3protein variant 1 gene
0.199% 28 3.319 J03037: Human carbonic anhydrase II mRNA
0.199% 31 2.979 D21261: Human mRNA for KIAA0120 gene
0.199% 31 3.542 L06797: HUMGPCR Human (clone L5) orphan G protein-coupled receptor mRNA
B    
  1. The 20 patients were grouped into early-stage (Stage I and II disease) category and late-stage (Stage III and IV disease) category. A; Similarly, patients without cervical nodal metastasis (N0) were compared to those with nodal disease (N1–N3). B; Genes whose expression in tumor was different in normal mucosa and which were most different between the clinical stage and nodal disease subgroups were identified by statistical regression analysis (t test). The genes identified within the two subgroups are listed. Note that HSAL2 were identified in both subgroups. Only genes that were present in at least 5 samples were included.