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Table 5 Correlation between sentinel lymph node (SLN) status and microvascular density (MVD), lymphovascular density (LVD) and intensity of VEGF-A

From: Immunostaining with D2–40 improves evaluation of lymphovascular invasion, but may not predict sentinel lymph node status in early breast cancer

Marker

 

All patients

SLN +

SLN -

pvalues*

VEGF-A a

Negative and weakly positive

37

13

24

0.32

 

Moderately positive

25

12

13

 
 

Strongly positive

30

6

24

 

MVD (CD34) b

 

79 (24–162)

79 (30–160)

81(24–162)

0.78

LVD (D2–40) b

 

7 (0–22)

8 (0–22)

7 (1–20)

0.73

  1. * adjusted for tumor size and age; a: values correspond to the number of patients in each group; b: values correspond to median vessel count; range is in parenthesis.