Figure 5

Western blot of histone modifications in mammary tumours. Western blot of acetylation, phosphorylation and methylation levels of histone H3 in mammary tumours after treatment with Rosiglitazone and Cisplatin in DMBA induced breast cancer rats. Where, lane a: Cancer Control, lane b: Rosiglitazone, lane c: Cisplatin and lane d: Rosiglitazone pre-treatment. Results were normalized with respect to total histone H3. Similar results were obtained in three independent set of experiments. All the values were represented as Mean ± S.E.M. (n = 3), **P < 0.01; * P < 0.05; a Vs Cancer Control and b Vs Cisplatin.