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Table 4 Prognostic impact (PI) of different tumor- and patient-related parameters

From: Prognostic scores in brain metastases from breast cancer

  n PI of hormone receptor status PI of HER-2 status PI of various factors (multivariate)
Claude et al. [10] 120 none no data performance status, lymphopenia
Bartsch et al. [16] 174 none none performance status, number of metast. sites
Le Scodan et al. [11] 117 receptor negative sign. worse none performance status, lymphopenia, hormone receptor status
Nam et al. [17] 126 receptor negative sign. worse HER-2 negative sign. worse number of metast. sites, age, hormone and HER-2 receptor status, leptomeningeal disease
Eichler et al. [18] 83 none HER-2 negative sign. worse HER-2 receptor status, number of brain metast., local disease control
Melisko et al. [19] 112 receptor negative sign. worse none hormone receptor status, age, performance status, stable or responding systemic disease
Harputluoglu et al. [20] 144 none none number of brain metast.
Park et al. [21] 125 none HER-2 positive sign. worse HER-2 receptor status, performance status
Altundag et al. [23] 420 receptor negative sign. worse none age, hormone receptor status
Wronski et al. [25] 70 receptor negative sign. worse no data leptomeningeal disease, combined surgery and whole brain radiotherapy
Lee et al. [22] 198 no data no data performance status, number of brain metast.
Viani et al. [9] 174 no data no data extracranial metastases, RPA class
Mahmoud-Ahmed et al. [12] 116 no data no data performance status
Liu et al. [24] 48 no data no data performance status, number of brain met.