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Figure 2 | BMC Cancer

Figure 2

From: The subcellular localization of IGFBP5 affects its cell growth and migration functions in breast cancer

Figure 2

Deletion of amino acids from 214 to 218 of IGFBP5 protein eliminates its nuclear localization. The wild-type (IGFBP5wt/pDsRed2-N1) or mutant (IGFBP5mt/pDsRed2-N1) fusion construct was transiently transfected into MBA-MD-435 breast cancer cells. The cells were fixed 48 h post-transfection and counterstained with DAPI. The images were taken by a fluorescence microscope at 63× magnification.

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