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Table 6 Activity of fotemustine according to the MGMT promoter methylation status

From: Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation

  Methylated MGMT Unmethylated MGMT Total pts
Partial Response 3 (1 GBM, 2 AA) - 3
Stable Disease 5 (3 GBM, 2 AA) - 5
Progression 4 (2 GBM, 2 AA) 7 (4 GBM, 2 AA, 1 AOA) 11
Total pts 12 7 19
  1. AA, anaplastic astrocytoma; AOA, anaplastic oligoastrocytoma, AOD, anaplastic oligodendroglioma; GBM, glioblastoma multiforme; MGMT, methylguanine methyltransferase; pts, patients