From: Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation
Group
Induction dose, mg/m2 (no. pts)
Maintenance dose, mg/m2 (no. of pts)
All pts no. = 40
A
65 (5)
75 (5)
5
B
75 (15)
75 (10) – 85 (5)
15
C
85 (10) – 100 (10)
75/85 (18) – 100 (2)
20