Figure 3

c-MYC siRNA-mediates a reduction in apoptotic cell death. Reduced apoptotic levels in cells transfected with c-MYC siRNA compared with control siRNA-transfected cells at 72 h post transfection. Values represent the mean absorbance of cytoplasmatic histone-associated DNA fragments (representative of two independent experiments, (n = 3; ± SD)). * Indicates a significant difference compared to control values, as determined by Student's t-test (***: P < 0.001, **: P < 0.01,*: P < 0.05).