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Table 3 Frequency of double haplotypes

From: Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

   Double haplotype frequencies (%) P value
Group Sample number -G -G -G +G -G -C -G +C +G -C +G +C -C -C -C +C +C +C All cases BRCA2+ BRCA-
Controls 112 55 (49.1) 2 (1.8) 21 (18.8) 25 (22.3) 0 0 2 (1.8) 6 (5.4) 1 (1.0) 0.98   
All cases 157 74 (47.1) 5 (3.2) 26 (16.6) 40 (25.5) 1 (0.6) 1 (0.6) 2 (1.2) 7 (4.5) 1 (0.6)    
BRCA1+ 42 18 (42.9) 2 (4.8) 7 (16.7) 11 (26.2) 0 0 1 (2.4) 3 (7.1) 0   0.94 0.61
BRCA2+ 57 26 (45.6) 2 (3.5) 12 (21.1) 11 (19.3) 1 (1.8) 1 (1.8) 0 3 (5.3) 1 (1.8)    0.34
BRCA- 58 30 (51.7) 1 (1.7) 7 (12.1) 18 (31.0) 0 0 1 (1.7) 1 (1.7) 0    
BRCA1/2+ 99 44 (44.4) 4 (4.0) 19 (19.2) 22 (22.2) 1 (1.0) 1 (1.0) 1 (1.0) 6 (6.1) 1 (1.0)    0.61