|  | Double haplotype frequencies (%) | P value | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group | Sample number | -G -G | -G +G | -G -C | -G +C | +G -C | +G +C | -C -C | -C +C | +C +C | All cases | BRCA2+ | BRCA- |
Controls | 112 | 55 (49.1) | 2 (1.8) | 21 (18.8) | 25 (22.3) | 0 | 0 | 2 (1.8) | 6 (5.4) | 1 (1.0) | 0.98 | Â | Â |
All cases | 157 | 74 (47.1) | 5 (3.2) | 26 (16.6) | 40 (25.5) | 1 (0.6) | 1 (0.6) | 2 (1.2) | 7 (4.5) | 1 (0.6) | Â | Â | Â |
BRCA1+ | 42 | 18 (42.9) | 2 (4.8) | 7 (16.7) | 11 (26.2) | 0 | 0 | 1 (2.4) | 3 (7.1) | 0 | Â | 0.94 | 0.61 |
BRCA2+ | 57 | 26 (45.6) | 2 (3.5) | 12 (21.1) | 11 (19.3) | 1 (1.8) | 1 (1.8) | 0 | 3 (5.3) | 1 (1.8) | Â | Â | 0.34 |
BRCA- | 58 | 30 (51.7) | 1 (1.7) | 7 (12.1) | 18 (31.0) | 0 | 0 | 1 (1.7) | 1 (1.7) | 0 | Â | Â | Â |
BRCA1/2+ | 99 | 44 (44.4) | 4 (4.0) | 19 (19.2) | 22 (22.2) | 1 (1.0) | 1 (1.0) | 1 (1.0) | 6 (6.1) | 1 (1.0) | Â | Â | 0.61 |