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Table 2 Frequency of IVS3+24 ins16 (+) allele

From: Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

   Genotypic frequencies (%) P values Allele frequencies (%) HWE
Group Sample number - - - + + + All cases BRCA2+ BRCA- - + P value
Controls 112 79 (70.5) 32 (28.6) 1 (0.9) 0.65    190 (84.8) 34 (15.2) 0.46
All cases 157 102 (65.0) 53 (33.8) 2 (1.2)     257 (81.8) 57 (18.2) 0.11
BRCA1+ 42 26 (61.9) 16 (38.1) 0   0.48 0.83 68 (81.0) 16 (19.0) 0.31
BRCA2+ 57 38 (66.7) 17 (29.8) 2 (3.5)    0.46 93 (81.6) 21 (18.4) 1
BRCA- 58 38 (65.5) 20 (34.5) 0     96 (82.8) 20 (17.2) 0.19
BRCA1/2+ 99 64 (64.7) 33 (33.3) 2 (2.0)    0.76 161 (81.3) 37 (18.7) 0.18