Table 2 Frequency of IVS3+24 ins16 (+) allele
| Â | Â | Genotypic frequencies (%) | P values | Allele frequencies (%) | HWE | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Group | Sample number | - - | - + | + + | All cases | BRCA2+ | BRCA- | - | + | P value |
Controls | 112 | 79 (70.5) | 32 (28.6) | 1 (0.9) | 0.65 | Â | Â | 190 (84.8) | 34 (15.2) | 0.46 |
All cases | 157 | 102 (65.0) | 53 (33.8) | 2 (1.2) | Â | Â | Â | 257 (81.8) | 57 (18.2) | 0.11 |
BRCA1+ | 42 | 26 (61.9) | 16 (38.1) | 0 | Â | 0.48 | 0.83 | 68 (81.0) | 16 (19.0) | 0.31 |
BRCA2+ | 57 | 38 (66.7) | 17 (29.8) | 2 (3.5) | Â | Â | 0.46 | 93 (81.6) | 21 (18.4) | 1 |
BRCA- | 58 | 38 (65.5) | 20 (34.5) | 0 | Â | Â | Â | 96 (82.8) | 20 (17.2) | 0.19 |
BRCA1/2+ | 99 | 64 (64.7) | 33 (33.3) | 2 (2.0) | Â | Â | 0.76 | 161 (81.3) | 37 (18.7) | 0.18 |