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Table 3 Factors influencing whether patients with SPN undergo at least one invasive test (Odds ratio [OR] and 95% confidence interval [CI]).

From: Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts

Factor n Unadjusted OR of receiving invasive test (CI)* Adjusted OR of receiving invasive test (CI)+ P $
Patient characteristics     
Age     
   35–65 52 0.8 (0.3–1.7) 1.5 (0.5–4.3) 0.38
   > 65 60 1 1  
Sex     
   Male 82 2.9 (1.2–7.2) 0.5 (0.1–3.8) 0.57
   Female 30 1 1  
Referral pattern     
   Specialist 94 4.1 (1.2–13.5) 6.6 (1.4–30.3) 0.01
   GP 18 1 1  
History of smoking     
   Current or past smoker 79 19.2 (5.3–68.8) 32.9 (4.3–247.7) <0.01
   Never smoked 33 1 1  
Nodule characteristics     
Calcification within the nodule     
Yes 12 0.1 (0.1–0.8) 0.5 (0.1–4.2) 0.54
No 100 1 1  
Spiculated nodule     
Yes 32 4.7 (1.8–11.8) 5.7 (1.6–19.5) <0.01
No 80 1 1  
Mediastinal involvement     
Yes 31 1.9 (0.8–4.6) 1.4 (0.4–4.3) 0.49
No 81 1 1  
  1. GP = general practitioner
  2. *In univariate logistic regression models
  3. +In multivariate logistic regression model
  4. $p values for the factors are the Wald statistics for the estimates in the model