Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

Figure 1

Induction of apoptosis in M14 melanoma cells by statins. M14 cells were exposed to statin treatment for 72 hours. Taxol (0.1 μM) was used as a positive control for apoptosis induction. Apoptosis was measured using an annexin V assay on the Guava EasyCyte, and results presented as % early and late apoptotic cells. (Lova = Lovastatin, Meva = Mevastatin, Simva = Simvastatin). Error bars represent std error of the mean for triplicate experiments. * indicates p < 0.05 using the Student's t-test to compare levels of late apoptosis in statin treated cells versus control.

Back to article page