Table 1 Presentation of the positivity indices (PI) of CD34, SMA and VEGF among the histological groups of study, in relation to MVD. CD34 and SMA reactivities are graded as negative (n), intermediate (i) and positive (p). VEGF expression is evaluated by the product of staining intensity score multiplied with the percentage of the staining area score. This product is graded as low (L), intermediate (I) and high (H).
STAINING | CD34 (n) | CD34 (i) | CD34 (p) | CD34 (PI) | SMA (n) | SMA (i) | SMA (p) | SMA (PI) | VEGF (L) | VEGF (I) | VEGF (H) | VEGF (PI) | MVD Mean(vessel number/mm2) ± SD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NORMAL (n = 20) | 0 | 0 | 20 | 1 | 16 | 4 | 0 | 0.2 | 18 | 2 | 0 | 0.1 | 86 ± 3 |
HUT (n = 32) | 0 | 0 | 32 | 1 | 30 | 2 | 0 | 0.062 | 32 | 0 | 0 | 0 | 79 ± 7 |
ADH (n = 22) | 1 | 1 | 20 | 0.954 | 21 | 1 | 0 | 0.045 | 13 | 3 | 6 | 0.409 | 119 ± 10 |
FA (n = 8) | 0 | 1 | 7 | 1 | 7 | 0 | 1 | 0.125 | 4 | 2 | 2 | 0.5 | 114 ± 9 |
DCIS-L (n = 21) | 0 | 4 | 17 | 1 | 14 | 6 | 1 | 0.333 | 5 | 12 | 4 | 0.761 | 121 ± 13 |
DCIS-I (n = 24) | 8 | 5 | 11 | 0.667 | 0 | 11 | 13 | 1 | 5 | 14 | 5 | 0.791 | 140 ± 32 |
DCIS-H (n = 33) | 25 | 5 | 3 | 0.242 | 0 | 0 | 33 | 1 | 6 | 11 | 16 | 0.818 | 146 ± 38 |
ALH (n = 11) | 0 | 0 | 11 | 1 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 109 ± 5 |
LCIS (n = 25) | 0 | 1 | 24 | 1 | 22 | 3 | 0 | 0.12 | 15 | 9 | 1 | 0.4 | 111 ± 7 |