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Table 4 Univariate and multivariate Cox survival analysis

From: Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognosis of invasive breast cancer

Univariate    
Variables p HR OS (95% CI)
Menopausal Status 0.215 0.958 (0.772–1.188)
Tumor Size 0.029 1.569 (1.264–1.946)
Lymph Node Status < 0.001 2.198 (1.860–2.596)
Histological Grade 0.045 1.438 (1.072–1.929)
ER 0.091 0.778 (0.579–1.042)
PR 0.046 0.687 (0.565–0.836)
Her-2/neu < 0.001 1.989 (1.684–2.349)
High Tumor MMP-13 0.007 1.357 (1.171–1.571)
High Stromal Fibroblast MMP-13 0.146 0.995 (0.786–1.259)
High Tumor-derived MMP-2 0.443 1.276 (0.969–1.678)
High Tumor-derived MMP-9 0.889 1.245 (0.984–1.575)
High Tumor-derived TIMP-1 0.023 1.278 (1.103–1.480)
High Tumor-derived TIMP-2 0.881 1.072 (0.842–1.364)
Multivariate    
Histological Grade 0.041 1.441 (1.074–1.933)
Lymph Node Status < 0.001 2.199 (1.861–2.598)
Her-2/neu < 0.001 1.98 (1.685–2.350)
Tumor Size 0.024 1.570 (1.266–1.948)
High Tumor MMP-13 0.006 1.565 (1.178–1.581)
High Tumor TIMP-1 0.021 1.281 (1.106–1.484)
  1. HR: Hazard Risk in Cox proportional hazard model analysis. HR > 1.0 means positive correlation with risk. HR < 1.0 means negative correlation with risk.