Skip to main content

Table 3 Correlation of MMP-13 expression with OS of overall and stratified subpopulations.

From: Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognosis of invasive breast cancer

   Tumor Stromal Fibroblast
  MMP-13SI n E OS (95% CI) p n E OS (95% CI) p
Overall          
  Low 133 20 153 (145~161) 0.0008 132 20 153(145~161) 0.0001
  High 127 47 107 (98~116)   125 48 106 (97~115)  
Node Status          
   Negative Low 82 8 135 (128~142) 0.3442 70 6 137 (131~143) 0.1231
  High 43 7 122 (115~129)   55 10 128/(119~137)  
   Positive Low 50 12 142 (127~158) 0.0041 45 13 136 (118~153) 0.0494
  High 82 40 93 (80~105)   87 39 97 (85~108)  
HER2/neu          
   Negative Low 113 14 157 (149~165) 0.0092 106 15 155 (145~163) 0.0446
  High 93 25 120 (111~129)   100 25 121 (113~130)  
   Positive Low 19 6 109 (85~133) 0.0154 9 4 96 (58~133) 0.5278
  High 32 22 69 (50~88)   42 24 81 (64~98)  
  1. OS: Months of overall survival; n: Number of patients; E: Events of positive stains; CI: confidence interval.