Table 3 Correlation of MMP-13 expression with OS of overall and stratified subpopulations.
| Â | Â | Tumor | Stromal Fibroblast | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | MMP-13SI | n | E | OS (95% CI) | p | n | E | OS (95% CI) | p |
Overall | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | Low | 133 | 20 | 153 (145~161) | 0.0008 | 132 | 20 | 153(145~161) | 0.0001 |
| Â | High | 127 | 47 | 107 (98~116) | Â | 125 | 48 | 106 (97~115) | Â |
Node Status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | Low | 82 | 8 | 135 (128~142) | 0.3442 | 70 | 6 | 137 (131~143) | 0.1231 |
| Â | High | 43 | 7 | 122 (115~129) | Â | 55 | 10 | 128/(119~137) | Â |
   Positive | Low | 50 | 12 | 142 (127~158) | 0.0041 | 45 | 13 | 136 (118~153) | 0.0494 |
| Â | High | 82 | 40 | 93 (80~105) | Â | 87 | 39 | 97 (85~108) | Â |
HER2/neu | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | Low | 113 | 14 | 157 (149~165) | 0.0092 | 106 | 15 | 155 (145~163) | 0.0446 |
| Â | High | 93 | 25 | 120 (111~129) | Â | 100 | 25 | 121 (113~130) | Â |
   Positive | Low | 19 | 6 | 109 (85~133) | 0.0154 | 9 | 4 | 96 (58~133) | 0.5278 |
| Â | High | 32 | 22 | 69 (50~88) | Â | 42 | 24 | 81 (64~98) | Â |