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Table 1 Occurrence of tumor growth in prostate and lymph node metastasis of in nude mice treated with alendronate (ALN) or saline (PBS)

From: Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

Treatment Occurrence of tumor growth in prostate (%) Occurrence of metastasis in prostate draining lymph nodes (%)
ALN 11/15 (73) 7/11 (64)
PBS 13/16 (81) 7/13 (54)
  1. Tumors were produced by orthotopic inoculation of 5 × 105 PC-3 cells and tumors were allowed to grow for 4 weeks.