Table 1 Clinical characteristics of included and excluded patients
Included (n = 100) | Excluded (n = 110) | p-value† | |
|---|---|---|---|
Age, median years (range) | 67 (27–92) | 71 (44–87) | ns |
Sex | ns | ||
Female | 17 (17 %) | 22 (20 %) | |
Male | 83 (83 %) | 88 (80 %) | |
Tumour site | |||
Glottic | 72 (72 %) | 61 (55 %) | 0.0188 |
Supraglottic | 20 (20 %) | 37 (34 %) | 0.0382 |
Subglottic | 4 (4 %) | 3 (3 %) | ns |
Transglottic | 4 (4 %) | 9 (8 %) | ns |
Stage | |||
0 | 3 (3 %) | 2 (2 %) | |
I | 57 (57 %) | 43 (39 %) | |
II | 22 (22 %) | 24 (22 %) | |
III | 9 (9 %) | 17 (15 %) | |
IV | 9 (9 %) | 24 (22 %) | 0.0010 |
Performance status WHO-Index | |||
0 | 77 (77 %) | 62 (59 %) | |
1 | 18 (18 %) | 25 (24 %) | |
2 | 4 (4 %) | 13 (12 %) | |
3 | 1 (1 %) | 4 (4 %) | |
4 | 1 (1 %) | 0.0016 | |
Married/Cohabitant | 70 (70 %) | 62 (56 %) | ns |
Smokers | 50 (50 %) | 70 (64 %) | ns |
Loss of weight | 21 (21 %) | 35 (32 %) | ns |
Residual disease | 2 (2 %) | 2 (2 %) | ns |
Cardiovascular disease | 45 (45 %) | 38 (35 %) | ns |
Other malignancy | 8 (8 %) | 11 (10 %) | ns |