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Figure 1 | BMC Cancer

Figure 1

From: Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

Figure 1

Immunohistochemical demonstration of EphA7 protein expression and blood vessels in GBM. Representative examples of GBM showing negative staining in tumor cells (A) or strong membranous and cytoplasmic staining in both tumor cells and endothelial cells (B). MVD in GBM by immunohistochemical staining for vWF, microvessels are represented by brown clusters, which stand out sharply from other tissues. Low tumor vascularity (C) in GBM with low expression of EphA7 as shown A. In contrast, microvessel density was relatively high (D) in GBM with high expression of EphA7 as shown B. Negative staining in normal brain tissue (E). Original magnification, ×400 (A, B, E) and ×200 (C, D).

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