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Table 1 Proliferation of tumour cell lines treated with PSK

From: The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis

 

Cell No. (Ă— 104)

% inhibition

Tumour cell line

Initial

Control

PSK1*

PSK2*

PSK1

PSK2

B16

25

220 ± 5

100 ± 2

92 ± 2

62

65

AGS

14

40 ± 1

18 ± 1

21 ± 1

84

71

Hela

25

180 ± 5

108 ± 4

91 ± 4

46

57

A549

25

260 ± 5

72 ± 2

104 ± 3

80

56

Jurkat

80

325 ± 5

224 ± 3

208 ± 3

41

47

B9

20

90 ± 4

75 ± 3

72 ± 3

22

26

Ando-2

15

30 ± 1

20 ± 1

22 ± 1

67

54

  1. *PSK1: 100 ÎĽg/ml; PSK2: 50 ÎĽg/ml. P < 0.001 versus control