Table 4 Tumor characteristics among 842 unselected breast cancer cases analyzed for NuMA A794G.
From: Comprehensive analysis of NuMAvariation in breast cancer
| Â | Â | NuMA A794G (2381C > G) | p | |
|---|---|---|---|---|
| Â | Total | CC | CG | Â |
Total | n = 889 | 837(94.2%) | 52(5.8%) | Â |
Histology | n = 889 | Â | Â | ND |
Ductal | Â | 599(71.6%) | 39(75.0%) | Â |
Lobular | Â | 132(15.8%) | 8(15.4%) | Â |
Medullary | Â | 11(1.3%) | 1(1.9%) | Â |
other | Â | 95(11.4%) | 4(7.7%) | Â |
Gradus | n = 793 | Â | Â | 0.107 |
1 | Â | 208(27.9%) | 7(14.9%) | Â |
2 | Â | 316(42.4%) | 26(55.3%) | Â |
3 | Â | 222(29.8%) | 14(29.8%) | Â |
pT Stage | n = 801 | Â | Â | 0.767 (Fisher) |
pT1-pT2 | Â | 699(92.6%) | 44(95.7%) | Â |
pT3-pT4 | Â | 56(7.4%) | 2(4.3%) | Â |
Lymph Nodes | n = 858 | Â | Â | 0.008 |
pN0 | Â | 446(55.3%) | 360(44.7%) | Â |
pN1-2 | Â | 19(36.5%) | 33(63.4%) | Â |
Estrogen Receptor Status | n = 845 | Â | Â | 0.691 |
Positive | Â | 622(78.4%) | 42(80.8%) | Â |
Negative | Â | 171(21.6%) | 10(19.2%) | Â |
Progesterone Receptor Status | n = 846 | Â | Â | 0.425 |
Positive | Â | 538(67.8%) | 38(73.1%) | Â |
Negative | Â | 256(32.2%) | 14(26.9%) | Â |
p53 Status | n = 653 | Â | Â | 0.035 |
Positive | Â | 132(21.3%) | 2(6.1%) | Â |
Negative | Â | 488(78.7%) | 31(93.9%) | Â |
Distant metastasis | n = 853 | Â | Â | 0.161 (Fisher) |
Positive | Â | 41(5.1%) | 0(0.0%) | Â |
Negative | Â | 765(94.9%) | 47(100.%) | Â |