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Table 4 Tumor characteristics among 842 unselected breast cancer cases analyzed for NuMA A794G.

From: Comprehensive analysis of NuMAvariation in breast cancer

   NuMA A794G (2381C > G) p
  Total CC CG  
Total n = 889 837(94.2%) 52(5.8%)  
Histology n = 889    ND
Ductal   599(71.6%) 39(75.0%)  
Lobular   132(15.8%) 8(15.4%)  
Medullary   11(1.3%) 1(1.9%)  
other   95(11.4%) 4(7.7%)  
Gradus n = 793    0.107
1   208(27.9%) 7(14.9%)  
2   316(42.4%) 26(55.3%)  
3   222(29.8%) 14(29.8%)  
pT Stage n = 801    0.767 (Fisher)
pT1-pT2   699(92.6%) 44(95.7%)  
pT3-pT4   56(7.4%) 2(4.3%)  
Lymph Nodes n = 858    0.008
pN0   446(55.3%) 360(44.7%)  
pN1-2   19(36.5%) 33(63.4%)  
Estrogen Receptor Status n = 845    0.691
Positive   622(78.4%) 42(80.8%)  
Negative   171(21.6%) 10(19.2%)  
Progesterone Receptor Status n = 846    0.425
Positive   538(67.8%) 38(73.1%)  
Negative   256(32.2%) 14(26.9%)  
p53 Status n = 653    0.035
Positive   132(21.3%) 2(6.1%)  
Negative   488(78.7%) 31(93.9%)  
Distant metastasis n = 853    0.161 (Fisher)
Positive   41(5.1%) 0(0.0%)  
Negative   765(94.9%) 47(100.%)  
  1. The mean age of diagnosis was 57 years for C:C, and 56 for C:G genotypes.