Table 3 Results from NuMA A794G screening
From: Comprehensive analysis of NuMAvariation in breast cancer
| Â | total | C:C | C:G | p 2 | OR2 | 95%CI |
|---|---|---|---|---|---|---|
Population controls | 906 | 853(94.2%) | 53(5.8%) | Â | Â | Â |
Unselected cases | 842 | 794(94.3%) | 48(5.7%) | 0.89 | 0.97 | 0.65–1.45 |
   bilateral breast cancer | 54 | 50(92.6%) | 4(7.4%) | 0.5413 | 1.35 | 0.47–3.92 |
   unilateral breast cancer | 788 | 744(94.4%) | 44(5.6%) |  |  |  |
   multiple cancers1 | 84 | 81(96.4%) | 3(3.6%) | 0.6173 | 0.59 | 0.18–1.93 |
   no multiple cancers | 758 | 713(94.1%) | 45(5.9%) |  |  |  |
Familial cases | 893 | 850(95.2%) | 43(4.8%) | 0.33 | 0.81 | 0.54–1.23 |
3+ families | 378 | 359(95.0%) | 19(5.0%) | 0.56 | 0.85 | 0.50–1.46 |
   breast cancer only | 298 | 283(95.0%) | 15(5.0%) |  |  |  |
   breast and ovarian cancer | 80 | 76(95.0%) | 4(5.0%) |  |  |  |
Small families | 515 | 491(95.3%) | 24(4.7%) | 0.34 | 0.79 | 0.48–1.29 |