Skip to main content

Advertisement

Table 3 Results from NuMA A794G screening

From: Comprehensive analysis of NuMAvariation in breast cancer

  total C:C C:G p 2 OR2 95%CI
Population controls 906 853(94.2%) 53(5.8%)    
Unselected cases 842 794(94.3%) 48(5.7%) 0.89 0.97 0.65–1.45
   bilateral breast cancer 54 50(92.6%) 4(7.4%) 0.5413 1.35 0.47–3.92
   unilateral breast cancer 788 744(94.4%) 44(5.6%)    
   multiple cancers1 84 81(96.4%) 3(3.6%) 0.6173 0.59 0.18–1.93
   no multiple cancers 758 713(94.1%) 45(5.9%)    
Familial cases 893 850(95.2%) 43(4.8%) 0.33 0.81 0.54–1.23
3+ families 378 359(95.0%) 19(5.0%) 0.56 0.85 0.50–1.46
   breast cancer only 298 283(95.0%) 15(5.0%)    
   breast and ovarian cancer 80 76(95.0%) 4(5.0%)    
Small families 515 491(95.3%) 24(4.7%) 0.34 0.79 0.48–1.29
  1. 1case with at least one other cancer than breast cancer
  2. 2compared to population controls, except comparisons between unilateral vs. bilateral and multiple cancers vs. one cancer
  3. 3Fisher's exact test
  4. No G:G genotypes were observed.