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Table 1 Association of different factors with acute leukemia in children from Mexico City

From: Father's occupational exposure to carcinogenic agents and childhood acute leukemia: a new method to assess exposure (a case-control study)

Variables Cases (N = 193) Controls (N = 193) Crude OR [95% CI]
  N % N %  
Type of leukemia      
   ALL 163 84.5    
   AML 30 15.5    
Institution      
   IMSS 122 63.2 124 64.2  
   SSa 71 36.8 69 35.8  
Family history of cancer 88 45.6 67 34.7 1.58 [1.05,2.38]
Sex: Male 110 57.0 115 59.6 0.90 [0.60,1.35]
Age: 2–5 years old 59 30.6 53 27.5 1.16 [0.75,1.81]
Child's weight at birth: >3,500 g 60 31.1 56 29.0 1.10 [0.71,1.71]
High crowding 80 41.5 71 36.8 1.22 [0.81,1.83]
Paternal age during pregnancy: >35 years old 26 13.5 24 12.4 1.10 [0.61,1.99]
Maternal age during pregnancy: >35 years old 13 6.7 16 8.3 0.80 [0.37,1.71]
Paternal alcohol consumption before pregnancy 172 89.1 172 89.1 1.00 [0.53,1.90]
Maternal alcohol consumption before pregnancy 139 72.0 154 79.8 0.65 [0.41,1.04]
Paternal cigarette smoking before pregnancy 118 61.1 105 54.4 1.32 [0.88,1.98]
Paternal cigarette smoking during pregnancy 107 55.4 88 45.6 1.49 [0.99,2.22]
Paternal cigarette smoking after pregnancy 117 60.6 110 57.0 1.16 [0.77,1.74]
Maternal cigarette smoking before pregnancy 35 18.1 49 25.4 0.65 [0.40,1.06]
Maternal cigarette smoking during pregnancy 7 3.6 10 5.2 0.69 [0.26,1.85]
Maternal cigarette smoking during breastfeeding 9 4.7 3 1.6 3.10 [0.83,11.62]
Exposure to carcinogenic agents at home 46 23.8 29 15.0 1.77 [1.06,2.96]
  1. ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; IMSS, Instituto Mexicano del Seguro Social; SSa, Secretaria de Salud; OR, odds ratio; CI, confidence interval