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Table 2 Multivariate Logistic Regression (MLR) analysis informed by CART for predicting NSLN metastasis among SLN+ patients (n = 213) (Bay Area SLN Database).

From: New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients

Variable or Composite Variable Significance Wald Statistic OR (95% CI)
Angiolymphatic Invasion 0.024 a a
Tumor Size 0.508 a a
Size of SLN Metastasis 0.173 a a
Angiolymphatic Invasion × Tumor Size 0.166 a a
Angiolymphatic Invasion × Size of SLN Metastasis <0.0001 52.7 4.73 (3.11–7.20)
Angiolymphatic Invasion × (Size of SLN Metastasis)2 0.041 a a
Tumor Size × Size of SLN Metastasis 0.888 a a
Tumor Size × (Size of SLN Metastasis)2 <0.0001 22.6 1.18 (1.10–1.26)
Tumor Size × Size of SLN Metastasis × Angiolymphatic Invasion 0.471 a a
Tumor Size × (Size of SLN Metastasis)2 × Angiolymphatic Invasion 0.761 a a
  1. OR: odds ratio; 95% CI: 95% confidence interval. a No Wald statistic or odds ratio calculated for variables not significant at P < 0.01 with respect to multivariate model