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Table 2 Incidence of amenorrhea

From: Incidence of reversible amenorrhea in women with breast cancer undergoing adjuvant anthracycline-based chemotherapy with or without docetaxel

 

6FEC 100

3FEC/3D

Amenorrhea at the end of chemotherapy

78 (93 %)

65 (92.8 %)

Clinically reversible amenorrhea (n = 154)

  

   Total population**

20/84 (23.7 %)

25/70 (35.5 %)

   Patients < 40 years (39)

13/18 (72 %)

15/21 (71.4 %)

   Patients ≥ 40 years (115)**

7/66 (10.5 %)

10/49 (20.5 %)

Recovery of premenopausal hormone values *

  

   Total population (n = 101)**

18/59 (29 %)

18/42 (42 %)

   Patients < 40 years (31)

11/15 (73.3 %)

12/16 (75 %)

   Patients ≥ 40 years (70)**

6/42 (14 %)

6/28 (21.4 %)

Clinically reversible amenorrhea. No hormone values available (n = 53)

  

   Patients < 40 years (8)

2/3 (66 %)

3/5 (60 %)

   Patients ≥ 40 years (45)**

1/24 (4 %)

4/21 (19 %)

  1. *within a year after the end of chemotherapy
  2. ** p < 0.05, chi-square