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Table 3 Association of molecular positivity in peripheral blood of breast cancer patients with traditional predictors of prognosis.

From: Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: Interim results of a prospective cohort study

Characteristic 5-gene panel (n = 136) mam(n = 29) PSE(n = 58)
Histologic Grade    
   I 31/63 (49.2%) 3/63 (4.8%) 15/63 (23.8%)
   II-III 98/143 (68.5%) 22/143 (15.4%) 42/143 (29.4%)
  P = 0.0083 P = 0.0315 P = 0.4110
Nodal Metastases (Path)    
   N0 97/150 (64.7%) 18/150 (12.0%) 46/150 (30.7%)
   N1 37/64 (57.8%) 10/64 (15.6%) 12/64 (18.8%)
  P = 0.3427 0.4715 P = 0.0726
ER Status    
   ER-neg 28/46 (60.9%) 10/46 (21.7%) 6/46 (13.0%)
   ER-pos 98/154 (63.6%) 17/154 (11.0%) 49/154 (31.8%)
  P = 0.7331 P = 0.0624 P = 0.0123
PR Status    
   PR-neg 40/67 (59.7%) 11/67 (16.4%) 12/67 (17.9%)
   PR-pos 79/120 (65.8%) 16/120 (13.3%) 42/120 (35.0%)
  P = 0.4033 P = 0.5650 P = 0.0134
Risk Category    
   Low/Intermediate Risk 20/34 (58.8%) 2/34 (5.9%) 9/34 (26.5%)
   High Risk 116/181 (64.1%) 27/181 (14.9%) 49/181 (27.1%)
  P = 0.5861 P = 0.2698* P = 0.9564
  1. P-values obtained by Chi-square analysis or *Fisher's exact test