Table 5 Effect of zosuquidar to the cytotoxicity of DNR, Mitox and Mylotarg in 31 AML patient cells
From: Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML)
Modulation* | No modulation | |
|---|---|---|
Active P-gp (D > 0.3) | 71% (5/7) | 29% (2/7) |
No active P-gp (D < 0.3) | 13% (3/24) | 87% (21/24) |