ERCC22251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: A preliminary study

Table 3 Comparison of genotype and allele frequencies (%) between Taiwanese colorectal cancer patients and those of other ethnic groups

Genotype	Caucasian	Japanese	Korean	Chinese	Taiwanese	Study data
GSTP1	Van der Logt ²⁶				Yeh ²⁷
AA	42.0	-	-	-	67.9	64.2
AG	47.4	-	-	-	28.7	32.8
GG	10.6	-	-	-	3.4	3.0
A allele	0.657	-	-	-	0.823	0.807
G allele	0.343	-	-	-	0.177	0.193
ABCB1	Kurzawski ²⁸	Komoto ²⁹	Bae ³⁰
CC	22.3	29.2	28.8	-	-	34.8
CT	44	58.3	56.8	-	-	51.8
TT	33.7	12.5	14.4	-	-	13.4
C allele	0.443	0.584	0.572	-	-	0.607
T allele	0.557	0.416	0.428	-	-	0.393
MTHFR	Curtin ³¹	Yin ³²	Kim ³³
CC	46	39.4	35.4	-	-	60.7
CT	45	48.2	50.2	-	-	35.8
TT	9	12.4	14.4	-	-	3.5
C allele	0.685	0.635	0.605	-	-	0.786
T allele	0.315	0.365	0.395	-	-	0.214
TYMS	Chen ³⁶	Kawakami ³⁴		Marsh ³⁵
3R/3R	32	69	-	67	-	67.2
2R/3R	50	27	-	31	-	29.3
2R/2R	18	4	-	2	-	3.5
3R allele	0.570	0.825	-	0.825	-	0.818
2R allele	0.430	0.175	-	0.175	-	0.182
ERCC2	Stoehlmacher ³⁷				Yeh ³⁸
AA	25	-	-	-	84	87.6
AC	61	-	-	-	15.6	11.9
CC	14	-	-	-	0.4	0.5
A allele	0.555	-	-	-	0.918	0.935
C allele	0.445	-	-	-	0.082	0.065
XRCC1	Stoehlmacher ³⁷		Hong ³⁹		Yeh ³⁸
GG	39	-	53.6	-	56.7	61.7
GA	52	-	42.1	-	36.2	31.8
AA	9	-	4.3	-	7.1	6.5
G allele	0.650	-	0.747	-	0.748	0.776
A allele	0.350	-	0.253	-	0.252	0.224

NOTE: author ⁿin this table is designated by a reference number (ⁿ) and the abbreviated name of the first author in the previously paper.

ISSN: 1471-2407