Figure 2
From: Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3
A. Effect of BADGE on cell metabolic activity. BADGE (10 μM) was added to cell cultures alone or 15 minutes before 100 μM RGZ. After 24 h, metabolic activity was determined by MTS assay. BADGE per se had no effect. BADGE + RGZ diminished metabolic activity compared to RGZ alone (*** p < 0.001). NO levels are shown between parentheses (μM). B. Effect of GW-9662 on LMM3 cells. GW-9662 (1, 10, and 20 μM) was added to cell cultures 1 h before 100 μM RGZ. After 24 h, metabolic activity was determined by MTS assay. (*** p < 0.001 vs. control untreated cultures).