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Table 2 The result of MSI, hypermethylation of MLH1 and IHC staining

From: Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer

IHC(-) MSH2 MSH6 MLH1 None Hypermethylation of MLH1
MSI-H 8* 4* 7 1 14
MSI-L 1 3 9 2 5
MSS 0 0 1 111 n.a.#
  1. *One MSI-H CRCs was negative both for MSH6 and MSH2
  2. # MLH1 promoter methylation was determined only in MSI CRCs.