Table 1 Activated protein levels in PDAC compared with histologically normal duct cells

p-JNK

≥ 2

77

4

<0.0001

p-ERK

≥ 2

62

8

<0.0001

p-SRC

≥ 2

73

40

0.0005

^S727 p-STAT3

≥ 3

38

4

0.005

^T308 p-PKB

≥ 2

69

12

<0.0001

p-S6K

≥2

27

16

0.5

^S473p-PKB

≥2

15

0

0.1

p-NFκB

≥2

19

4

0.2

p-S6

≥2

54

40

0.4

p-p38

≥ 2

65

20

0.002

^Y705 p-STAT3

≥ 2

85

26

0.0005

p-GSK3β

≥ 3

50

12

0.006

p-mTOR

≥ 3

19

0

0.05

p-RAF

≥ 3

62

24

0.01

p-βCAT

≥ 2

42

96

<0.0001

p-NFκB

≥3

50

56

1

p-ERK

≥ 3

62

16

0.001

p-p38

≥ 3

62

20

0.004

p-JNK

≥ 3

26

0

0.01

^T308p-PKB

≥3

27

8

0.1

^S727p-STAT3

≥2

77

80

1

^S473 p-PKB

≥ 2

62

16

0.001

^Y705p-STAT3

≥2

69

56

0.4

p-βCAT

≥2

35

32

1

p-GSK3β

≥1

23

20

1