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Figure 2 | BMC Cancer

Figure 2

From: Flow-cytometric monitoring of disease-associated expression of 9-O-acetylated sialoglycoproteins in combination with known CD antigens, as an index for MRD in children with acute lymphoblastic leukaemia: a two-year longitudinal follow-up study

Figure 2

Detection of MRD as indicated in the R3 region. A representative profile of a B-ALL patient presenting the status of triple positive cells detected in R3 region viz. OAcSGP+CD10+CD19+ or OAcSGP+CD34+CD19+ at the diagnosis is shown in PB (a) and BM (d). After the completion of 5 weeks of treatment, the BM sample first received (as per protocol) is compared with PB. The MRD (%) of these samples is shown in PB (b) and BM (e) and MRD during CR is shown in PB (c) and BM (f). Similarly, the representative profile of a T-ALL patient shows the percentage of OAcSGP+CD7+CD3+ cells at diagnosis in PB (g) and BM (j) respectively. MRD (%) in PB and BM is shown in (h, k) after 5 weeks of treatment and (i, l) during CR. PB and BM from B-ALL patient and T-ALL patient are abbreviated as PBB-ALL, BMB-ALL, PBT-ALL and BMT-ALL respectively.

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