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Table 4 Intratumoral genomic heterogeneity and diagnostic performance of the mini-array

From: The development of a mini-array for estimating the disease state of gastric adenocarcinoma by array CGH

 

Case No.

Total

 

S39

B17

C22

I87

S50

 

Method 1

      

Node metastasis

-

+ (1)

-

-

+ (2)

3/20

Liver metastasis

-

-

-

-

-

0/20

Peritoneal dissemination

-

-

-

-

-

0/20

Early or advanced

+ (1)

-

-

+ (1)

-

2/20

Histologic type*

+ (1)

-

-

-

+ (2)

3/20

Method 2

      

Node metastasis

-

-

-

+ (1)

-

1/20

Liver metastasis

-

-

-

-

-

0/20

Peritoneal dissemination

-

-

-

-

-

0/20

Histologic type*

-

-

-

+ (1)

-

1/20

  1. The difference in diagnosis was rare between four samples from the same tumor. In particular, there were no BAC clones affecting the estimation of liver metastasis and peritoneal dissemination in all of the samples.
  2. -; Absence of intratumoral genomic heterogeneity affecting diagnosis
  3. +; Presence of intratumoral genomic heterogeneity affecting diagnosis (the number of clones different from others)
  4. * Intestinal or diffuse type