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Table 3 Relative gene expression in tumor tissue (vs. β-actin)

From: Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine

Molecular Marker

TS

DPD

TP

ERCC1

Metastasis (No.)

65

63

64

64

Median (range)

3.91 (0.81–77.58)

1.62 (0.15–11.89)

5.64 (1.06–31.89)

2.17 (0.34–8.23)

25th%, 75th%

2.38, 6.31

0.92, 3.04

3.77, 10.34

1.48, 3.36

Primary (No.)

24

21

24

25

Median (range)

2.07 (0.5–4.49)

0.36 (0.15–1.41)

3.23 (0.71–10.02)

1.04 (0.34–3.28)

25th%, 75th%

1.26, 2.58

0.21, 0.55

1.54, 4.98

0.64, 1.55