Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer

BMC Cancer

Table 2 Patient survival in dependence of clinico-pathological parameters and HDAC isoform expression

Parameters	No. of cases	No. of events	Two Year survival time (± SE) in months	p-value
HDAC1 expression				0.285
low	47	12	76.6 (± 6.2)
high	59	10	83.1 (± 4.9)
HDAC2 expression				0.235
low	46	12	76.1 (± 6.3)
high	60	10	83.3 (± 4.8)
HDAC3 expression				0.906
low	92	19	80.5 (± 4.1)
high	14	3	78.6 (± 11.0)
Age				0.119
≤ 61	49	7	85.7 (± 5.0)
>61	57	15	75.4 (± 5.7)
pT stage				<0.001
pT1	53	2	96.2 (± 2.6)
pT2	3	1	66.7 (± 27.2)
pT3	47	17	66.0 (± 6.9)
pT4	3	2	33.3 (± 27.2)
Histological grade				<0.001
G1	11	0	-
G2	74	12	85.1 (± 4.1)
G3	17	7	58.8 (± 11.9)
G4	4	3	25.0 (± 21.7)
pN status				0.001
pN0	50	10	80.0 (± 5.7)
pN1/2	12	8	41.7 (± 14.2)
Metastasis				<0.001
M0	47	5	89.4 (± 4.5)
M1	23	14	43.5 (± 10.3)
Ki-67 index				0.931
≤ 10%	70	15	80.0 (± 4.8)
>10%	36	7	80.6 (± 6.6)

ISSN: 1471-2407