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Figure 6 | BMC Cancer

Figure 6

From: Role of cAMP in the promotion of colorectal cancer cell growth by Prostaglandin E2

Figure 6

Effect of EP3 receptor selective agonists on Lovo cell proliferation and cAMP signalling. A HT-29 cells were deprived of serum and stimulated with 10 nM PGE2, 10 μM butaprost, 10 μM sulprostone or 10 μM 11-deoxy-PGE1. DNA synthesis was monitored 5 days later. Data are mean ± S.E.M. of cells/well of 3 experiments with triplicate measurements. B Serum-starved HT-29 cells were stimulated for 20 min with the same agonists as in A followed by measurement of cAMP levels. Student's t test: P values ***P < 0,001, **P < 0,01, *P < 0,05.

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