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Table 3 Comparison of F-based group vs. G-based group

From: Gemcitabine-based versusfluoropyrimidine-based chemotherapy with or without platinum in unresectable biliary tract cancer: a retrospective study

Characteristics

F Group (%)

G Group (%)

P value

Total Number

144

99

 

Median age, years (range)

60 (range 29–80)

61 (range 26–81)

 

Sex

  

0.831

   Male

95 (66.0)

64 (64.6)

 

   Female

49 (34.0)

35 (35.4)

 

ECOG performance status at baseline

  

0.06

   0 – 1

132 (91.7)

83 (83.8)

 

   ≥ 2

12 (8.3)

16 (16.2)

 

Disease

  

0.966

   Intrahepatic cholangiocarcinoma

54 (37.5)

38 (38.4)

 

   Gallbladder cancer

42 (29.2)

30 (30.3)

 

   Extrahepatic bile duct cancer

36 (25.0)

22 (22.2)

 

   Ampulla of Vater carcinoma

12 (8.3)

9 (9.1)

 

Relapsed disease

51 (35.4)

33 (33.3)

0.737

Biliary stent or bypass during treatment

31 (21.5)

33 (33.3)

0.04

Disease associated infection during treatment (cholangitis, liver abscess)

31 (21.5)

31 (31.3)

0.086

Duration from off chemotherapy to death

3.5 months (95% CI, 2.9–4.0)

3.3 months (95% CI, 2.2–4.3)

0.752

  1. ECOG, Eastern Cooperative Oncology Group; F, fluoropyrimidines; G, gemcitabine; CI, confidence interval